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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
09/03/2000 |
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Data da última atualização: |
31/03/2017 |
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Autoria: |
LIFSCHITZ, A.; VIRKEL, G.; IMPERIALE, F.; SUTRA, J. F.; GALTIER, P.; LANUSSE, C.; ALVINERIE, M. |
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Título: |
Moxidectin in cattle: correlation between plasma and target tissues disposition. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Journal Veterinary Pharmacology and Therapeutics, v.22, p.266-273, 1999. |
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Idioma: |
Inglês |
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Conteúdo: |
The time of parasite exposure to active drug concentrations determines the persistence of the antiparasitic activity of endectocide compounds. This study evaluates the disposition kinetics of moxidectin (MXD) in plasma and in different target tissues folloeing its subcutaneous (s.c.) administration to cattle. Eighteen male, 10-month old Holstein calves weighing 120-140 kg were subcutaneously injected in the shoulder area with a commercially available formulation of MXD (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) at 200 ug/kg. Two treated calves were killed at each of the following times post-treatment: 1, 4, 8, 18, 28, 38, 48, 58 and 68 days. |
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Palavras-Chave: |
Parasita; Parasite. |
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Thesagro: |
Gado; Plasma. |
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Thesaurus Nal: |
cattle; moxidectin. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01347naa a2200265 a 4500
001 1799788
005 2017-03-31
008 1999 bl --- 0-- u #d
100 1 $aLIFSCHITZ, A.
245 $aMoxidectin in cattle$bcorrelation between plasma and target tissues disposition.
260 $c1999
520 $aThe time of parasite exposure to active drug concentrations determines the persistence of the antiparasitic activity of endectocide compounds. This study evaluates the disposition kinetics of moxidectin (MXD) in plasma and in different target tissues folloeing its subcutaneous (s.c.) administration to cattle. Eighteen male, 10-month old Holstein calves weighing 120-140 kg were subcutaneously injected in the shoulder area with a commercially available formulation of MXD (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) at 200 ug/kg. Two treated calves were killed at each of the following times post-treatment: 1, 4, 8, 18, 28, 38, 48, 58 and 68 days.
650 $acattle
650 $amoxidectin
650 $aGado
650 $aPlasma
653 $aParasita
653 $aParasite
700 1 $aVIRKEL, G.
700 1 $aIMPERIALE, F.
700 1 $aSUTRA, J. F.
700 1 $aGALTIER, P.
700 1 $aLANUSSE, C.
700 1 $aALVINERIE, M.
773 $tJournal Veterinary Pharmacology and Therapeutics$gv.22, p.266-273, 1999.
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Registro original: |
Embrapa Pantanal (CPAP) |
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| Registros recuperados : 1 | |
| 1. |  | MORENO, L.; ECHEVARRIA, F. A. M.; MUÑOZ, F.; ALVAREZ, L.; SANCHEZ BRUNI, S.; LANUSSE, C. Dose-dependent activity of albendazole against benzimidazole-resistant nematodes in sheep: relationship between pharmacokinetics and efficacy. Experimental Parasitology, v. 106, n. 3-4, p. 150-157, 2004.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Embrapa Pecuária Sul. |
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| Registros recuperados : 1 | |
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